SAFC Sigma Aldrich

3050 Spruce Street
St. Louis
MO 63103
United States

+1 314 534 4900



SAFC is the custom manufacturing and services business unit of Sigma-Aldrich Corporation. We are recognised as a top 10 global fine molecule supplier and trusted manufacturer of speciality chemicals and biologics for the life science and high technology industries.


Utilising distinctive technologies and competencies, SAFC is focused on developing tailored solutions that resolve development and manufacturing challenges in order to accelerate speed to market. Our rich portfolio includes high-purity inorganic materials for high technology applications, cell culture products, services for biopharmaceutical manufacturing and biochemical production, and complex, multi-step organic synthesis of APIs and key intermediates.

SAFC is a complete pipeline partner for pharmaceutical and biopharmaceutical companies developing and commercialising complex small-molecule APIs and biologic drug products. The company combines world-class, 'single point of contact' project management with proven processes and procedures that support all stages of drug development. From pre-clinical through commercialisation, we enable customers to bring their products to market in the most efficient timeframe possible.

With SAFC's broadly integrated portfolio of services and state-of-the-art global manufacturing capabilities, our scientific and production experts are highly qualified to analyse projects, consider issues and propose problem-solving ideas. Their experience comes from traditional APIs and biologic manufacturing as well as industry-leading emerging technologies, including:

  • High-potency APIs
  • Solid-state chemistry research
  • Viral products
  • Chemical-biologic API conjugation