Copley launches compact units for testing transdermal drug delivery systems

Published: 15-Jan-2009

Copley Scientific, the Nottingham, UK and Switzerland-based manufacturer of inhaler test equipment, has introduced two compact instrumentation units for testing transdermal drug delivery systems.

Copley Scientific, the Nottingham, UK and Switzerland-based manufacturer of inhaler test equipment, has introduced two compact instrumentation units for testing transdermal drug delivery systems.

The units are based on the vertical diffusion or Franz cell, a well-established method for in vitro testing of topical pharmaceutical semi-solid dosage forms, such as creams, ointments and gels. Streamlined heating systems and a novel clamping arrangement simplify equipment set-up and enhance measurement accuracy, the company says.

The robust and compact HDT 10 accommodates 10 diffusion cells in a single aluminium heating block. Powerful magnetic stirrers are located beneath each test station, with stirrer speed and temperature set, controlled and displayed from a single control panel. The heating block design gives stable temperature control and eliminates the ‘spaghetti’ of tubing associated with the use of more-conventional water-jacketed cells.

The HDT 1 is a smaller, lower cost unit with just a single cell. It is particularly useful during early phase evaluation studies when there is little material available and the testing burden is lighter, the company says. The cell design is identical to the HDT 10 and incorporates a three-pronged spring clamp that makes it easier to eliminate air bubbles during test set-up, for better quality data.

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