Shimadzu’s i-Series Plus expands the product line and improves performance and user friendliness, resulting in better reproducibility and measurement accuracy, minimising human error, to ensure reliable data in the analysis of pharmaceuticals and foods
The new i-Series Plus integrated HPLC significantly improves analytical productivity with automated pretreatment operations. The i-Series Plus consists of the compact HPLC Prominence-i and UHPLC system Nexera-i
With the i-Series Plus, pretreatment operations have been automated, such as the processes to dilute samples and add reagents. This results in less mistakes and measurement errors and ensures highly reproducible and reliable data in the analysis of pharmaceuticals and foods.
The i-Series Plus is a compact solution, covering conventional to ultrafast LC analysis.
Application-specific solutions are available within the product range such as the cannabis analyser for potency testing of primary active components of cannabis for medical use. It offers a simple procedure, complete with a column, methods, batches and report templates.
i-Series Plus also offers compliance features satisfying the data integrity requirements of the pharmaceutical industry.
Since the release of i-Series systems in 2014, 10,000 units have been sold around the world. i-Series systems have been used for research and development activities, specification tests and quality control operations in a wide range of application fields, such as pharmaceutical, chemical and food industries.
The new system is equipped with a function to automate sample pretreatment, which serves to minimise operator mistakes and measurement errors, improve separation of the target components and to enhance sensitivity.
Core features are:
1. Automated sample pretreatment operations
The system has pretreatment functions to adjust the samples before starting analysis, including processes to dilute the target component contained in the sample to be measured and to add a certain amount of a reaction reagent to detect the target component with high sensitivity.
The system can automatically dilute samples up to 100 times. Automated reagent addition allows a wider range of components to be analysed directly. For example, amino acid components in foods can be analysed in a short time with high sensitivity.
2. Support of data integrity features for the pharmaceutical industry
There have been a number of cases that do not satisfy the requirements for data integrity as specified by regulatory agencies, making pharmaceutical manufacturers concerned about this issue.
Strict observation of the requirements for analytical data management (attributable, legible, contemporaneous, original, accurate) is demanded.
Analytical instruments are required to have a function to limit orphan data (measurement results that can be acquired, or actions that can be performed without leaving records on the instrument). The i- Series Plus has a mode to inhibit orphan data. Both the instrument and software support data integrity.