Market Reports

Peak identification by LC/MS: Automation versus analyst

High pressure liquid chromatography/mass spectrometry (LC/MS) is an important technique that facilitates the correct and accurate identification of impurities in pharmaceutical products and intermediates

Testing the limits of dosage production with continuous direct compression technology

GEA’s Dr James Holman, Head of New Development and Innovation, Pharma, discusses the process robustness and operational considerations of the company’s CDC 50 platform during a 120-hour trial run

Beximco Pharma: The Bangladeshi company connecting with the US

COO Rabbur Reza talks about the strategy behind approaching pharmaceutical manufacturing from an emerging market

Addressing the need for cost-effective vaccine manufacturing

Process intensification and integrated continuous bioprocessing are two approaches that can be used to achieve cost-effective, local production of high-quality biologic products. Tania Pereira-Chilima, Product Manager at Univercells, explains

Future market dynamics and opportunities in immuno-oncology

Long-term survival, tumour-agnostic effects and the potential for cure in a fraction of patients are key catalysts driving the explosion of research and recent approvals in IO. Dr Kevin Robinson recently caught up with SmartAnalyst’s Nidhi Dhingra and Jaideep V. Thottassery to delve a little deeper

A microfluidic approach to production of alginate beads for cell encapsulation

Gurinder Vinner, Material Scientist at Dolomite Microfluidics, discusses the benefits of continuous microfluidic production for the encapsulation of mammalian cells with no loss of viability

The case for single-use architecture in pharma

Billy Sisk, Life Sciences Industry Manager, EMEA, at Rockwell Automation recently contributed to the free downloadable e-book, the <i>Big Book of Biotech</i>, alongside input from GSK, Merck, ZeClinics and others. Here, for readers of <i>Manufacturing Chemist</i>, he picks up his topic of single-use facilities

Case Study: Phase I to commercial in 18 months

Gabor Heltovics, Druggability Technologies CEO, talks about using Quotient Sciences to progress and scale-up an improved pain relief drug formulation

Manufacturing misconceptions: The difficulties of tackling big data analysis

The advent of Industry 4.0 offers huge potential to explore new and exciting changes to the manufacturing floor, comments Dirk Ortloff, Department Manager, camLine

Guide to wash-in-place process in horizontal mixing systems

Modular solutions are proven to reliably fulfil any industry-specific requirements in the pharmaceutical, food, cosmetics, and chemical industries. Sebastian Steinkamp of Lödige provides a step-by-step guide to effective cleaning

Stainless steel products in contemporary bioprocessing

ASEPCO's Mark Embury on the shift from stainless steel to single-use systems in the pharmaceutical manufacturing sector

A rules-based approach to labelling and artwork management: Part I

Many organisations today are experiencing unprecedented demands from regulatory authorities and consumers alike for product labelling to be made clearer and more informative, says Graham Francis, Channel Marketing Manager, Kallik

A new approach to molecular imaging in cancer patients

A variety of different imaging approaches, spanning molecular to whole-body scans, have contributed greatly to our understanding of the conditions required for an effective anticancer immune response, reports Ian Wilson, CEO, ImaginAb

Unlocking R&D potential with equipment expertise

Worldwide, pharmaceutical manufacturers face a daunting challenge: that of reconciling ever-higher cost pressures with increased quality requirements

Taking a multifaceted approach to combatting superbugs

Paul Chapman, Partner at Marks & Clerk LLP, takes a look at research underway for testing a compound on Gram-negative bacteria known for being the most difficult to treat of all infections

Seal selection for pump optimisation

Process containment and reducing the risk of product contamination are key requisites for pharmaceutical production equipment. Yet the industry is notoriously averse to change when it comes to the selection of mechanical seals and seal materials, says John Smiddy, European Business Development and Technical Support Director for AESSEAL

Integrated tools for upstream process intensification: Part I

Changes to bioprocessing methodologies are driven by the need for increased speed, a lower cost of goods and greater flexibility, writes Gerben Zijlstra, Global Technology Consultant at Sartorius Stedim Biotech

The future of supply chain management in pharmaceuticals

Global regulations and local legislation have made serialisation in the pharmaceutical industry standard practice. And, although serialisation is now commonplace, the supply chain is still beset with potential issues such as counterfeit products, says Andreas Bechthold, General Manager, Mettler-Toledo

Recombinant cultures for superior enzyme output

A non-GMP enzyme manufacturing process at Porton Biopharma has been converted from native production to recombinant using bioinformatics and next-gen sequencing. David Gervais, Head of Product and Fermentation Development, explains the method

Preparing for the paradigm shift in bioprocessing

While upstream titers have improved dramatically over the last decade, downstream processing has remained relatively unchanged. Now is the time to push efficiencies, and Renaud Jacquemart explains how the Natrix technology could offer a helping hand

Advances in biopharmaceutical manufacturing control strategies

The inherent complexity of biopharmaceutical products presents an ongoing challenge for manufacturers, particularly in the drive towards continuous manufacturing operations, writes Dr Richard Moseley, Chief Technologist, Microsaic Systems

Harnessing dark data in early stage drug development

A 1966, anticipating the impact of rapid advances in computing, a <i>Time</i> magazine article hypothesised: “By 2000, the machines will be producing so much that everyone in the US will, in effect, be independently wealthy. How to use leisure time will be a major problem.” Graeme Dennis, Commercial Director of Preclinical Pharma, IDBS, reports

Single-pass tangential flow filtration: A versatile approach to streamlining biomanufacturing

Current trends in the biopharmaceutical industry are driving the implementation of high capacity processes that are capable of reducing costs and equipment footprint without sacrificing manufacturing efficiency and product quality

Review: Cannabis Europa 2019

Scientists, businesspeople and politicians backing the regulation of medical and recreational cannabis have taken the stage of Southbank Centre this week to discuss research and business opportunities

Trending Articles

  1. Outsourcing in pharma: a comprehensive guide to strategic advantages and considerations Outsourcing in pharma drives agility, compliance, and efficiency—NSF delivers expert audits, training, remediation, and embedded support
  2. Recombinant versus synthetic peptide synthesis: the perks and drawbacks Since the introduction of novel peptide drugs into the market, the demand for polypeptide manufacturing has significantly increased, reports Dr Philipp Markolin
  3. Poolbeg granted FDA Orphan Drug Designation for POLB 001 The US FDA grants orphan status to support the development of medicines for rare disorders affecting fewer than 200,000 people in the US
  4. Peak identification by LC/MS: Automation versus analyst High pressure liquid chromatography/mass spectrometry (LC/MS) is an important technique that facilitates the correct and accurate identification of impurities in pharmaceutical products and intermediates
  5. The economic advantages of continuous flow chemistry Batch production has been the traditional workhorse of the pharmaceutical manufacturing sector. However, economic advantages are taking continuous flow out of the realm of a niche technology for high energy, hazardous reactions to become an essential part of the small molecule manufacturing toolkit

Upcoming event

POWTECH

23-25 September 2025 | Exhibition | Nuremberg, Germany See all