Lonza’s new GS System medium and feed platform reaches 10g/L
Customers realise higher product yields, improved cellular metabolism, a more reliable process and lower total cost of goods
Lonza is launching a new cell culture medium and feed platform for the GS Gene Expression System that achieves product yields up to 10g/L. The CDACF ‘Version 8’ platform, together with the GS System, forms the backbone of Lonza’s robust and reliable mammalian production technology.
‘Lonza understands the need to innovate and help our growing GS customer base realise immediate cost savings during early-phase development,’ said Janet White, head of Lonza Development Services. ‘We are very confident that this latest improvement to our GS System will be a significant advancement for mammalian bioproduction.’
The Version 8 platform incorporates GS-CHO-specific CDACF cell culture medium, feed base powders and supplements and will be globally manufactured and supplied by Lonza’s media production facilities. Developed with Lonza’s extensive experience in biological manufacturing, the CDACF Version 8 platform realises higher product yields and improved cellular metabolism to achieve a more robust process.
Lonza has also successfully used the CDACF Version 8 medium and feed platform with DHFR-CHO cell lines. The Version 8 platform is available to all holders of the GS Gene Expression System. Lonza will continue to support all media customers including those currently implementing the Version 6 protein-free system and the Version 7 CDACF system.
