OET signs two research agreements to expand flashBAC system

Published: 26-Nov-2009

Will expand OET\'s flashBAC baculovirus protein expression systems


Oxford Expression Technologies (OET), a UK provider of baculovirus-based protein expression products and services, has signed r&d agreements with US firms ParaTechs and LifeSensors, which will expand OET's flashBAC baculovirus protein expression systems.

OET's flashBAC technology is a recombinant system that can express large amounts of multiple recombinant viruses in a one-step process. The company says it is suitable for small- and large-scale protein expression and enables scientists to produce proteins faster, more easily and cost-effectively.

The collaboration with ParaTechs, based in Lexington, Kentucky, will investigate the impact on quality and yield of expressing a Vankyrin gene in tandem with a foreign gene and evaluate whether using the flashBAC system enhances any benefits. This project will also compare flashBAC vectors expressing Vankyrin gene-fusions in ParaTechs" Vankyrin-enhanced cell lines, with standard insect cell lines.

OET and Malvern, Pennsylvania-based LifeSensors will work together to incorporate a SUMO (small ubiquitin-like modifier) tag into the flashBAC system, and evaluate whether this increases the quality of protein produced.

OET was recently named "Best Early Stage Biotech" at the Oxford and South-East Bioscience Awards in the UK, in recognition of its introduction of technology with commercial value and development of a revenue stream.

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