CPTx and NanoCell awarded EU funding for in vivo CAR T therapy with immune-silent single-stranded DNA

Published: 15-Aug-2025

The QUIET-CAR project that targets cancer and autoimmune diseases is top-ranked among the 120-plus Eurostars Grant submissions

CPTx, a biotechnology company developing in vivo genetic medicines built with programmable single-stranded DNA (ssDNA), announces that the QUIET-CAR collaborative project with NanoCell Therapeutics has received a Eurostars Grant from the European Union through the Horizon Europe programme and Eureka Network.

The focus of the QUIET-CAR project is the development of targeted lipid nanoparticles carrying novel immune-silent ssDNA for in vivo CAR T therapy.

"CPTx is committed to bringing in vivo CAR T therapies to patients through our proprietary pipeline development programmes and now also through the QUIET-CAR project with NanoCell,” said Hendrik Dietz, CEO of CPTx.

“The QUIET-CAR project represents another innovative approach to CAR T, and we look forward to advancing it together."

"Being selected from so many high-quality submissions underscores the promise of the project and the strength of our technology."

Eurostars, part of the European Partnership on Innovative SMEs and supported by Horizon Europe, is a funding initiative to accelerate transnational innovation.

With participation from 37 countries, the programme selects only the most promising technological breakthroughs, evaluated by independent experts.

The selection of the CPTx/NanoCell project from more than 120 proposals reflects QUIET-CAR’s strong scientific and clinical potential across oncology and autoimmune diseases.

NanoCell Therapeutics is a privately held biotechnology company pioneering transformative in vivo cell engineering through its non-viral, DNA-based gene therapy platform, primarily targeting oncology and autoimmune diseases.

Read more about CPtx's research here.

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