How onco-HPAPI manufacturing is adapting to a new era

By Kevin Robinson | Published: 18-Jul-2025

The oncology landscape is undergoing a quiet but powerful shift. Pharmaceutical companies, once focused primarily on novel compounds, are now increasingly exploring repurposing opportunities with existing high-potency oncology APIs (onco-HPAPIs)

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Manufacturers are seeing a steady rise in requests to reformulate these potent actives; sometimes it’s to address new cancer types, other times it’s to change delivery routes from, for example, injectable to oral.

These shifts, although subtle, are symptomatic of broader changes in drug development: there’s a greater emphasis on speed and cost-efficiency.

Dr Kevin Robinson spoke to K.H. Honneshaiah (KHH), Head of API and Chief Operating Officer, Shilpa Pharma Life Sciences, to find out more. 

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