Increasing efficacy in oral solid dose drug delivery

Published: 29-Jul-2025

Using excipients that are well-suited for extended-release profiles in oral solid dosage forms can help to enhance a drug’s therapeutic effect and improve patient compliance

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Oral solid dosage forms offer a variety of release profiles for specific therapies. Yet, fine-tuning the exact delivery method can be an obstacle for manufacturers, notes Jim Baxter, North America Technical Business Development Manager at Lubrizol.

Extended-release (ER) oral solid dose tablets provide an effective solution when drug release is required for a longer time or as a preferred option to increase patient compliance — a growing challenge when creating therapies that meet patient needs.

The National Institutes of Health (NIH) found that 75% of patients failed to take their medication as directed, potentially leading to suboptimal treatment outcomes. 

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