Thermo Fisher Scientific and Xcell Biosciences have entered into a collaboration to advance cell and gene therapy research.
Focused on regulatory T cells (Tregs) and tumour-infiltrating lymphocytes (TILs) the companies will aim to advance these therapies — particularly in the field of autoimmune and solid tumours.
While significant progress has been made in the CAR-T space, Thermo Fisher wanted to focus on these two up-and-coming modalities, which could be used to treat millions of patients worldwide.
With solid tumors representing approximately 90% of adult cancers and instances of autoimmune diseases on the rise worldwide, this collaboration looks to target a crucial area for improving global health.
This joint research project will focus on developing new methodologies to enhance the efficacy of Tregs and TILs as therapeutics.
The companies will also look to steamline workflows, while finding ways to improve scalability and reproducibility in cell therapy manufacturing, making these treatments more accessible to patients.
“We are thrilled to collaborate with Thermo Fisher Scientific on groundbreaking research opportunities," commented Xcellbio's Chief Technology Officer, Shannon Eaker.
"By leveraging our AVATAR™ cell therapy manufacturing platform, we aim to push the boundaries of what is possible in cell and gene therapy. This partnership will enable us to develop more effective treatments for patients in need.”
“Xcellbio's interest in utilising our Gibco CTS Detachable Dynabeads platform within Thermo Fisher Scientific’s modular, closed and automated cell therapy manufacturing workflow is a testament to the strength of our technologies,” said Andy Campbell, senior director of research and development at Thermo Fisher Scientific.
“In combination with our full portfolio, including the Gibco CTS DynaCellect Magnetic Separation System and the Gibco CTS Rotea Counterflow Centrifugation System, we are confident that this collaboration will significantly shorten and enhance the manufacturing workflow for cell therapies in this space, ultimately helping our customers make the world a healthier place.”
