Orla Protein Technologies, a protein surface company based in Newcastle-upon-Tyne in the UK, has introduced a series of specialist cell culture surfaces which allow researchers and manufacturers to maximise the biological activity of various growth factor proteins without the need to add them to the culture media.
The OrlaBoost animal-free protein surfaces comprise tethered growth factors and cytokines that are immobilised on the surface of the culture medium, rather than being held in suspension.
The company says this ensures maximum stability, optimising research and manufacturing efficiencies by eliminating the need to add expensive growth factors to the cell culture media.
Developed using the patented OrlaSurf technology, the company claims traditional limitations in the manufacture and immobilisation of proteins on surfaces have been overcome. This means the surfaces can be used in basic cell biology research and can be cost effectively scaled-up for cell manufacturing.
In this way, the OrlaBoost range mimics natural interactions and provides consistent growth media for research biology, regenerative medicine, biomedical and large scale cell culture applications.
The OrlaBoost range includes ECM proteins and growth factors. They are supplied as pre-coated plates individually wrapped and ready for use and other formats, including flasks, can also be provided.
