Orla Protein Technologies, a UK developer of protein surfaces for cell biology, assay development, biochips and manufacture, has devised an efficient and economical means of determining the optimum protein surface required for different cell culture applications and research tasks.
OrlaExplorer plates provide specialised animal-free surfaces providing combinations of ECM proteins and growth factors to explore, screen and identify the most effective coating for specific experiments and research requirements.
Specific cell types can be tested against a range of proteins and protein mixtures, enabling the optimum coating to be determined, with the desired protein mixture then being supplied pre-coated to most multi-well plate and flask formats.
Using patented OrlaSurf advanced cell culture technology, the immobilised surface proteins supplied on the OrlaExplorer plates provide reliable, consistent and scaleable growth media.
Specialist surfaces can be coated with attachment factors, growth factors, differentiation factors, or cytokines – mixed in different combinations or ratios to produce multi surface formats to meet precise functional requirements. This also enables the creation of arrays, patterns and gradients on cell culture surfaces.
The OrlaExplorer screening surfaces comprise 32 different combinations of proteins for easy testing and optimisation purposes.
Examples include specific test combinations for the enhanced attachment, growth and maintenance of osteoblasts, MSCs and related cells, for pluripotent stem and iPS cells, and for neuronal cells, neural progenitor/stem cells and related cells.
Orla’s advanced proteins can be used to produce highly customised surfaces on laboratory glass and plasticware, gold analytical biochips and TiO2 for precise assay development, cell biology, regenerative medicine and large-scale cell culture applications.
