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Market Reports

Stainless steel products in contemporary bioprocessing

ASEPCO's Mark Embury on the shift from stainless steel to single-use systems in the pharmaceutical manufacturing sector

A rules-based approach to labelling and artwork management: Part I

Many organisations today are experiencing unprecedented demands from regulatory authorities and consumers alike for product labelling to be made clearer and more informative, says Graham Francis, Channel Marketing Manager, Kallik

A new approach to molecular imaging in cancer patients

A variety of different imaging approaches, spanning molecular to whole-body scans, have contributed greatly to our understanding of the conditions required for an effective anticancer immune response, reports Ian Wilson, CEO, ImaginAb

Unlocking R&D potential with equipment expertise

Worldwide, pharmaceutical manufacturers face a daunting challenge: that of reconciling ever-higher cost pressures with increased quality requirements

Taking a multifaceted approach to combatting superbugs

Paul Chapman, Partner at Marks & Clerk LLP, takes a look at research underway for testing a compound on Gram-negative bacteria known for being the most difficult to treat of all infections

Seal selection for pump optimisation

Process containment and reducing the risk of product contamination are key requisites for pharmaceutical production equipment. Yet the industry is notoriously averse to change when it comes to the selection of mechanical seals and seal materials, says John Smiddy, European Business Development and Technical Support Director for AESSEAL

Integrated tools for upstream process intensification: Part I

Changes to bioprocessing methodologies are driven by the need for increased speed, a lower cost of goods and greater flexibility, writes Gerben Zijlstra, Global Technology Consultant at Sartorius Stedim Biotech

The future of supply chain management in pharmaceuticals

Global regulations and local legislation have made serialisation in the pharmaceutical industry standard practice. And, although serialisation is now commonplace, the supply chain is still beset with potential issues such as counterfeit products, says Andreas Bechthold, General Manager, Mettler-Toledo

Recombinant cultures for superior enzyme output

A non-GMP enzyme manufacturing process at Porton Biopharma has been converted from native production to recombinant using bioinformatics and next-gen sequencing. David Gervais, Head of Product and Fermentation Development, explains the method

Preparing for the paradigm shift in bioprocessing

While upstream titers have improved dramatically over the last decade, downstream processing has remained relatively unchanged. Now is the time to push efficiencies, and Renaud Jacquemart explains how the Natrix technology could offer a helping hand

Advances in biopharmaceutical manufacturing control strategies

The inherent complexity of biopharmaceutical products presents an ongoing challenge for manufacturers, particularly in the drive towards continuous manufacturing operations, writes Dr Richard Moseley, Chief Technologist, Microsaic Systems

Harnessing dark data in early stage drug development

A 1966, anticipating the impact of rapid advances in computing, a <i>Time</i> magazine article hypothesised: “By 2000, the machines will be producing so much that everyone in the US will, in effect, be independently wealthy. How to use leisure time will be a major problem.” Graeme Dennis, Commercial Director of Preclinical Pharma, IDBS, reports

Single-pass tangential flow filtration: A versatile approach to streamlining biomanufacturing

Current trends in the biopharmaceutical industry are driving the implementation of high capacity processes that are capable of reducing costs and equipment footprint without sacrificing manufacturing efficiency and product quality

Review: Cannabis Europa 2019

Scientists, businesspeople and politicians backing the regulation of medical and recreational cannabis have taken the stage of Southbank Centre this week to discuss research and business opportunities

Register now: Lab Innovations celebrates Year of the Periodic Table

Event in Birmingham will feature 35 hours of educational CPD-accredited seminars and the Cleanroom Hub in partnership with <em><a href='http://www.cleanroomtechnology.com'>Cleanroom Technology</a></em> magazine

CMC strategies for the acceleration of commercial-ready ADC manufacturing

The potential for antibody-drug conjugate (ADC) programmes to accelerate from early to late stage clinical development highlights the need to establish commercial launch-ready manufacturing early and efficiently, reports Courtney Morgret, Senior Scientist, Manufacturing Sciences, AbbVie

Video: Silverson manufactures 19ft Duplex Disintegrator mixer in-house

Multimedia showcases the largest batch mixer in the Silverson range as it comes to life

ECH Medical to open the UK's first standalone cannabis clinic

Company has also facilitated the import of the UK's first bulk shipment of cannabis-based medicine

Blockchain: the key to a secure pharmaceutical supply chain

Pharmaceutical companies are increasingly exploring solutions to combat counterfeiters, reports Tom Egan, Vice president, Industry Services, PMMI, Rick Fox, President and CEO, FOX IV Technologies, and Bill McBeath, Chief Research Officer, Chainlink Research

GEA supplies Bracco with falling film evaporator for contrast media

The evaporator Bracco has ordered is specifically designed for use in the production of Iodoftal

Delivering higher value diagnostics

Dr Kevin Robinson had a discussion with Ann Costello, Global Franchise Lead, Centralised Solutions at Roche Diagnostics, following EuroMedLab, regarding how enhancing lab technology, including automated maintenance, is helping to reduce manual operations and the risk of errors

The future of pharmacovigilance and the impact of automation

Pharmacovigilance (PV), the process of identifying, tracking, evaluating and preventing negative outcomes from drug therapies, is a sector that has seen huge growth in recent years. David J. Balderson, Vice President, Global Safety Operations, Sciformix, a Covance company, reports

Butterfly valves: Containment and monitoring for API transfer

Michael Avraam of Chargepoint Technology writes about systems that are critical to preventing HPAPIs harming staff and the bottom line

Establishing a secure supply chain for phyto-APIs

APIs produced from naturally derived materials can be challenging to supply reliably and with consistently high quality. C<sup>2</sup> PHARMA has implemented multiple solutions to ensure supply chain security
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Trending Articles

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    Overcoming the hurdles of strategic market expansion Ramprasad Kaparaboyena, Regulatory Affairs Manager and QP for Pharmacovigilance at Gaelic Laboratories, discusses how to overcome the challenges of expanding your pharma market into new global regions
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    Reimagining biosimilars: faster access, stronger supply, sustainable healthcare Outdated development models, uneven adoption and policy barriers are holding Europe back. Dr Kevin Robinson (KSR) spoke to Matt Erick (ME), Head of Advanced Markets at Biocon Biologics (pictured), to discover how the industry can close the biosimilars void and unlock billions in savings
  3. Reading and understanding vendor-supplied tablet drawings Understanding the tablet drawings supplied by tooling vendors is a meaningful way to learn more about your product, reports John Norman, Technical Service Representative, Natoli Engineering Company
  4. Peak identification by LC/MS: Automation versus analyst High pressure liquid chromatography/mass spectrometry (LC/MS) is an important technique that facilitates the correct and accurate identification of impurities in pharmaceutical products and intermediates
  5. Freeze drying ADCs: points to consider for industrial applications As antibody-drug conjugates gain momentum in the pharmaceutical industry, manufacturers are increasingly looking to implement safe and effective process trains to produce them. Lyophilisation experts at GEA Pharma & Healthcare assess some of the most critical challenges and how to overcome them

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