Boosting productivity through novel biocatalysis partnership

Published: 10-Dec-2014

Use of new biocatalysts is making many industrial processes more effcient. Dr Jim Lalonde, Senior Vice President, R&D, Codexis, looks at the logistics and drivers behind pharma’s increasing interest in biocatalysis for drug development and manufacturing

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In July 2014 Codexis, a biotechnology company based in Redwood City, California, US, granted GlaxoSmithKline (GSK) a licence to use its CodeEvolver platform technology to develop novel enzymes for use in the manufacture of GSK’s human pharmaceutical and healthcare products. As part of the agreement, which is worth US$25m plus milestones and potential royalties, the CodeEvolver protein engineering platform will be installed at GSK’s research and development site at Upper Merion, Pennsylvania.

This is the first time that Codexis has licensed its protein engineering platform technology to any party in the healthcare field, but it is likely to be the first of a series of similar licences as the pharma industry increasingly recognises the advantages of incorporating enzymatic processes into the manufacture of drugs.

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