Zetasizer AT offers automated online nanoparticle sizing for process monitoring

Device uses dynamic light scattering (DLS) to automatically measure size of nanoparticles in suspensions and emulsions

The Malvern Zetasizer AT

Malvern Instruments has added the new Zetasizer AT, a robust, online, automated analyser that uses dynamic light scattering (DLS) to automatically measure the size of nanoparticles in suspensions and emulsions to its portfolio.

The new analyser provides timely and reliable data that enables tracking of processes in the sub-micron size range, such as emulsification, dispersion, milling and homogenisation, while at the same time eliminating the delays and inefficiencies associated with manual analysis.

The UK firm says the net result is improved process understanding, streamlined process development and improved product quality.

In many applications, particle size is a critical determinant of nanoparticle performance. When producing nanoparticles or droplets via size reduction, detecting the endpoint of a batch process or tracking stable conditions during continuous production in a timely manner is important.

'The introduction of an online DLS system is an important advance for those developing and manufacturing nanoparticles,' said Alon Vaisman, Product Development Manager, Process Systems at Malvern Instruments.

'The ability to measure particle size in a timely way, using a well-established and popular method enables more precise trending of size changes, supporting faster, more robust process development and competitive well-controlled manufacture, whether batch or continuous.'

The Zetasizer AT builds on Malvern’s Zetasizer Nano DLS technology. The mobile, fully automated, computer-controlled sampling system enables measurements across the size range 1–1000nm and can be easily operated in research laboratories as well as on the manufacturing floor.

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