Ready-to-use kit enabled lentivirus titre determinations during the manufacture of lentivirus vectors
Gyros Protein Technologies, a pioneer in automated nanolitre-scale immunoassays and leading provider of peptide synthesisers and reagents, today announced the introduction of Gyrolab p24 Kit, for lentivirus titre determination in lentivirus vector manufacturing.
The new Gyrolab p24 Kit adds to the company's range of ready-to-use kits and Gyrolab Bioaffy CDs which are used by scientists and bioengineers in the rapidly growing cell and gene therapy market, where lentivirus vectors are commonly used to transport therapeutic genes.
Gyrolab p24 Kit offers high throughput and automated analyses, producing results 24 times faster than ELISA, to accelerate lentivirus bioprocess workflows and reduce time to market. The kit also enables high-quality data to be generated from small sample volumes, requiring 10 times less sample compared to ELISA. Additionally, minimal matrix interference reduces the need for dilution, increasing sensitivity and accuracy.
Kyriacos Mitrophanous, CSO of Oxford Biomedica, said: "Efficient bioprocessing, bioanalytical development, and manufacture of lentivirus vectors is vital for the advancing field of cell and gene therapy, which is creating an array of potential new treatment options for patients."
"A recent report highlighted that there are currently 289 novel cell and gene therapies in development for a variety of diseases and conditions, around 40% of which are targeting cancers. We're pleased to see Gyros Protein Technologies developing vital products to support this field," Mitrophanous said.