CoreRx, a Florida, USA based contract R and D lab, was created to fill a recognised need for API formulation design and delivery support for early phase pharma research, specifically for phase I-III clinical trials.
Originally, it invested in an instrument valued at more than $300,000 for capsule filling but had technical challenges with the unit, which halted production and cost them a project.
The company’s lead metrologist turned to Mettler Toledo for a solution and discovered that Quantos could substantially increase CoreRx’s capsule fill rate with a dosing tolerance of 1%.
Compared to the first capsule-fill unit, Quantos was a fraction of the cost and size, easy-to-use and able to be serviced in-house.
The first project in which Quantos was used puportedly allowed the company to fill capsules at a rate five times higher than their previous process.
CoreRx then added the Quantos Handheld Powder Dispensing (HPD) unit as a portable and fully-contained way to handle APIs in their labs.
This helped production, as many projects start with only a few grams of API. The HPD enables formulation experts to make single analytical samples, supporting seamless technology transfer and scale-up.
Today, CoreRx’s services have grown to include the entire spectrum of cGMP solutions for pharmaceutical applications.
In this fast-paced, expanding environment, the company’s lead formulation scientist particularly appreciates Quantos' sample-to-sample traceability.
