Misconceptions in high pressure homogenisation

Following on from its Introduction to High Pressure Homogenisation guide, Biopharma have released a misconceptions edition to explore some of the most common mistakes or assumptions associated with high pressure homogenisation

High pressure homogenisation involves subjecting a liquid sample to high pressures by forcing it through a very narrow orifice, via a high pressure pump.

This induces very high shear upon the sample, which, in turn, disrupts the particles.

Applications of this technology include emulsification, cell disruption, particle size reduction and unilamellar liposome preparation.

This reflects a level of versatility that has generated a great deal of popularity within both industrial and academic environments related to pharmaceutical, biotechnological and chemical processing.

Achievement of optimal results relies on exposing a particular sample to conditions, which the user knows will not impact the product in a negative way ie not exerted to a greater pressure than deemed suitable.

This is mainly due to the fact that different particle types behave differently, as a result of their size, shape, charge, density and other factors.

This booklet aims to address some of the most common misconceptions encountered by users. Click here to download the full guide.

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