Phenomenex, global researcher, designer and manufacturer of technologies for the separation sciences, has introduced new mixed-mode selectivities and particle sizes for UHPLC, HPLC (Ultra/High Performance Liquid Chromatography) and preparative work in the Luna column family.
The first is the new Luna Omega Polar C18 stationary phase, a selectivity on an silica particle that delivers a wide elution window and combined high retention for polar and nonpolar analytes.
This new phase is 100% aqueous-stable due to a polar-modified surface, providing flexibility in solvent and gradient system selection needed to achieve desired polar/non polar analyte separation.
The Luna Omega Polar C18 is offered in a high-performance 1.6 microns particle for UHPLC instruments as well as a low-pressure 5 microns particle for direct scalability to analytical HPLC or preparative work. The 5 microns particle is available in Phenomenex's Axia-packed preparative columns.
Luna Omega PS C18
Phenomenex has also introduced the 100% aqueous-stable Luna Omega PS C18 that delivers two distinct separation mechanisms at the same time.
The particle surface of the PS C18 contains a positive charge that facilitates greater acidic compound retention through ionic interaction, while the C18 ligand delivers general reversed-phase retention.
This mixed-mode selectivity is a tool for separation of compound mixtures that have varying functional groups, such as peptides, pesticides or metabolite profiles. Additionally, the positive surface charge encourages excellent basic compound peak shape through the ionic repulsion of these compound species.
Uses
Luna Omega columns are well suited for a range of applications, including drug discovery and development, food contaminant analysis, environmental testing, toxicology and clinical research.
Phenomenex Kinetex Core-Shell Technology and Luna Omega columns together provide a complementary UHPLC solution for greater efficiency and separation power.
With a growing range of valuable selectivities, this pairing of core-shell and fully porous UHPLC products affords a better choice for immediate gains in productivity, resolution and retention.
Combining the Luna Omega Polar C18 with the previously released fully porous Luna Omega 1.6 microns C18 and Kinetex 1.7 microns core-shell phases further expands the options for UHPLC method development and improvement.