Romaco focuses on R&D at the AAPS Annual in San Diego, US

Romaco will exhibit Romaco Kilian and Romaco Innojet, technologies for pharmaceutical manufacturers’ at the AAPS Annual in San Diego, US, 12–15 November

L-R: Romaco Kilian STYL’ONE tableting robot, Romaco Innojet Ventilus V 2.5 laboratory-scale processing machine

Romaco Kilian STYL’ONE Evolution tableting robot

This tableting robot has been equipped with a whole set of new features for a broad array of R&D applications. The compression cycles have been sped up by more than 60% and the maximum compression force increased to 50 kN to simulate high speed presses.

Compression force profiles for all standard rotary presses can now be determined, for instance for the Romaco Kilian KTP 420X at up to 104 revolutions per minute. ANALIS, the intelligent PAT software, calculates all relevant tableting parameters based on compression force or displacement controlled cycles.

The remarkable precision of the test batches — whether mono-layer, multilayer or core tablets — means powder properties can be analysed very realistically.

This scalable tableting robot can also be utilised to optimise existing processes or troubleshoot errors. The STYL’ONE Evolution boasts a maximum output of 1750 tablets an hour.

The ROCO Pack software, enables the tableting robot to simulate the operation of granulating mills. The new models have a fully interchangeable process worktable, which is a great advantage if the products in question are highly abrasive.

Romaco Innojet VENTILUS V2.5

The laboratory-scale version of the Romaco Innojet VENTILUS V2.5 is used for granulating, drying and coating particles of any size from 10 μm to 2 mm. Its enhanced processing efficiency and the special VENTILUS design, means that 25% shorter batch times are achieved compared to conventional technologies.

The homogeneous flow conditions in the cylindrical product container enable extremely gentle intermixing of the product. The process air is controlled by the ORBITER booster, an ingenious container bottom consisting of overlapping circular plates.

Together with the ROTOJET, the central bottom spray nozzle, the ORBITER booster forms a unique functional unit that meets all the requirements for linear scale-ups.

The innovative air flow bed technology ensures accurate control of the product movement and equally precise application of the spray liquids. The resulting formulations can achieve the required release profile with between 10 and 15% less spray liquid.

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