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Market Reports
Cell and gene therapies: on the brink of commercialisation
With their one-and-done potential and pinpoint targeting capability, cell and gene therapies (CGTs) offer huge promise in the fight against a range of previously untreatable diseases. Yet, investment in this sector is not taken lightly. Typically, developers must invest billions of dollars in therapies that might take 10 years to reach the market as they battle the odds against high failure rates
Inspiration from unexpected places
How pharmaceutical companies can learn from advances in nicotine delivery
Overcoming hurdles in the biopharmaceutical pipeline with advanced analytics
In conversation with Nick Pittman and Magnus Wetterhall, both Global Marketing Managers, Bioprocessing, at Waters Corporation, Dr Kevin Robinson explored some of the big issues associated with manufacturing biologics, how they can be overcome and what Waters is doing to help scientists expedite the process of developing new therapies for patients in need
Treating infection with precise medicine may prevent our next pandemic
Antimicrobial resistance (AMR) is a grave concern that the scientific and medical community have been warning the public about for decades. There have been no new antibiotics for 35 years and no truly effective incentive for drug makers to develop them, making this threat even more urgent. As the COVID-19 pandemic demonstrated, preparedness could save countless lives and the world’s economy
Optimising coating process parameters and formulation concepts for functional taste-masking during continuous manufacturing
This article describes work done to optimise the coating process parameters (spray rate, inlet air temperature, inlet airflow), formulation and functionality of a taste-masking coat for oral solid dosage forms during continuous production
Dissolution testing: an established technique driving advances in drug delivery
This article introduces dissolution testing and highlights its ability to support modern formulation challenges. Pharmacopoeial methods are discussed with reference to specific apparatuses and method parameters. Dissolution testing equipment from Copley Scientific is showcased to illustrate the performance and productivity that are accessible with well-designed, cost-effective solutions
COVID-19: focusing attention on the next transformation in healthcare
The lightning-fast global spread of the Omicron variant of COVID-19 was a painful reminder that the only way to protect against the disease is vaccination on a global level. At the same time, South African researchers’ quick identification and analysis of Omicron demonstrated the strength and interconnectedness of the international science community, with critical data rapidly passed to those who were best able to mount a response
Manufacturing Chemist LIVE 2022 in review (part I)
Taking a front row seat during the two-day pharmaceutical conference in Birmingham, UK, Dr Kevin Robinson reports on what’s new, emerging and exciting in the world of drug delivery and beyond
Native mass spectrometry as a drug discovery engine
Using mass spectrometry to characterise and screen large intact protein targets, captured directly in their native state, is making waves as a differentiated approach to hit finding in drug discovery, explains Dr Jonathan T.S. Hopper, founder and VP of Platforms at OMass Therapeutics
Transforming tomorrow
Shaping the future with better processes, GEA has responded to the impact that digitalisation is having on the pharmaceutical manufacturing industry and pioneered a suite of virtual technologies that improve the customer experience
Chemistry meets biology: an integrated approach to developing and manufacturing medicines of the future
Until recently, chemists and biologists rarely needed to collaborate to develop a new large molecule drug, reports Chris Conway, President, Research and Development, Curia
Closing the gap between biotherapies and their quality control
NGS-based biosafety tests are giving the biomanufacturing industry a facelift
Droplet microfluidics: leveraging the untapped potential of single-cell research and high-throughput screening
The age of personalised medicine requires modern tools. Recent research breakthroughs such as the meteoric rise of CRISPR technology and the emergence of single-cell sequencing have clearly shown a vast untapped potential in the life sciences, reports Juozas Nainys, CEO of Droplet Genomics
A smart approach to ready-to-use drug containment solutions
At a time when global healthcare providers are coming under previously unknown levels of pressure, their suppliers need to react with greater speed and flexibility to meet demand without compromising patient safety
Influence of material and capsule filling process on DPI aerosolisation performance
The effect of capsule filling parameters on emitted dose and fine particle fraction by a DPI was investigated using a benchtop capsule filling device. Compression was the parameter that affected weight and emitted fraction the most, whereas the type of coarse lactose seems to influence the fine particle fraction
Bringing biotech to the Baltics: the rise of Lithuania
Lithuania’s biotechnology competencies lie in cell and gene therapies, enzymes and the wider pharmaceutical industry, offering companies a rich pool of talent in a still-unsaturated market. Dr Kevin Robinson spoke with the country’s Minister for Economy and Innovation, Aušrinė Armonaitė, to find out more
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From stockpiles to smart supply chains: how industry wants to fix Europe’s drug shortages
An EU-level stockpile may work, but only if it’s flexible, closely monitored and built with logistics in mind. Industry players say drug security will depend less on volume and more on data, digital oversight and early collaboration throughout the supply chain
A grandmaster’s approach to successful tableting
Tableting is a fundamental unit operation in the production of pharmaceutical oral solid dosage forms. Despite its long history of use and the development of innovations such as extended dwell times, unique technologies that independently and simultaneously measure and control both tablet weight and hardness, and a weight control system that provides increased sensitivity at lower forces, production problems still occur. Here, Dr Harald Stahl, Group Director, Application and Strategy Management, GEA, provides some troubleshooting tips from an unlikely source: the chess board
The modularisation of chemical API synthesis
The modularisation of chemical synthesis pathways in pharmaceutical production can improve overall plant efficiency and reduce planning time. Glatt Ingenieurtechnik has optimised the active pharmaceutical ingredient (API) synthesis process and developed bespoke plant designs for several international customers
Leaders of transformation
Haig Armaghanian, founder and CEO of Haig Barrett, explores how synthetic biology pioneers are revolutionising therapeutic development
Is the production of biologic drugs ready for an overhaul?
Is the industry ready for a new manufacturing model? Mark Emalfarb, President and CEO of Dyadic International, thinks so and explains why to Dr Kevin Robinson
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6–8 October 2026 | Exhibition | Fiera Milano, Italy
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