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Trends in the manufacturing of viral gene therapeutics and next generation vaccines

Gene therapy is still an experimental technology, but the dangers are now much better understood, according to Jeff Strobel, site director, SAFC Carlsbad, CA

Handling protocols: key consideration in HPAPI market

Over the past 10 years, the manufacture of highly potent APIs has become increasingly attractive to contract manufacturers, says Trevor Calkins, director of process development, SAFC

Linking biological molecules to highly potent APIs

Antibody-drug conjugate technology is the ‘smart bomb’ in the arsenal of weapons used to target cancer cells, says Cynthia Wooge, SAFC process development manager

IR spectroscopy on the move

Perkin Elmer\'s latest spectrometer, Spectrum Two, brings spectroscopy to the non-specialist

Temperature tracking

As clinical trial sites move to distant geographic areas and more biologics are involved, temperature monitoring of drug shipments becomes a growing need. Almac has responded with a system it believes will transform temperature monitoring for clinical trials

Case study: Five years of trouble-free manufacturing for large pharma company

Alkermes, through the merger with Elan Drug Technologies, to become Alkermes plc, has been developing and manufacturing commercial scale solid oral dosage products for more than 40 years. This case study demonstrates a large pharmaceutical contract manufacturing engagement in which there has been five years trouble-free supply with OTIF (On-Time-In-Full) consistently >95%.<br> Process and product improvement initiatives were also delivered, which enabled significant capacity and yield improvements. These improvements resulted in significant cost savings for our partner.

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From powder to granules: a deep dive into wet granulation methods

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