Bayer and Memory sign licence deal
US drug development company Memory Pharmaceuticals, of New Jersey, has signed a license agreement with Bayer for the exclusive and worldwide rights to commercialise and market MEM 1003, a new-generation drug candidate to treat dementia.
Mem1003 belongs to the class of neuronal calcium channel modulators that aims at down-regulating pathologically elevated intracellular calcium levels indicated in neurological disorders such as vascular dementia (VaD) and Alzheimer's disease. Elevated calcium levels can be harmful and ultimately lead to cell death. This new-generation calcium channel modulator is said to regulate elevated intracellular calcium levels back to normal physiological levels to restore proper functioning and to protect neurons from calcium overload.