Bayer Technology Services launches thin capsule formulations

Bayer Technology Services will be introducing its novel micrometer-thin capsule formulations for inhalable medications.

A coating just a few thousandths of a millimeter thick can neutralise the taste of medications formulated as particles capable of penetrating the lungs, enabling bitter-tasting substances to be inhaled.

The technology is based on a precipitation process with which hydrophobic materials can be applied to the surface of active ingredients. These materials prevent the active substance from being wetted rapidly and thus from being released in the mouth and throat. The active substance is not released until it reaches the lungs or stomach. Special capsule formulations can be tested rapidly for a wide variety of active substances in screening studies.

This technology can also be used to improve formulations for oral administration. Particle size plays a decisive role in ensuring good bioavailability. In addition, particles smaller than 50µm are not perceived as powder by the taste sensors, so the individual does not find them unpleasant in chewable tablets.

Hall 9.1, Stand B33