Cellexus Biosystems, a UK-based specialist in the design, manufacture and commercialisation of novel disposable technology for growing cells, has sold a CellMaker Lite2 disposable bioreactor to its first customer in Ireland.
The customer is Dr Amir Khan, a principal investigator at Trinity College in Dublin. Dr Khan is using the system to grow E. coli to produce proteins for structural studies.
"The production of milligram amounts of recombinant human proteins in E. coli for subsequent purification, crystallisation and X-ray structure determination is essential for the research goals of my laboratory," said Dr Khan. "The CellMaker Lite2 was an attractive option over vessel fermentors for its ease-of-use and minimal maintenance requirements for my small research group.
"The utility of the system has already been demonstrated in the case of a marginally folded protein, whose levels of soluble expression exceeded those of traditional shaker-incubators by 3-4 fold in our hands."