EnBioTec and Peakdale develop nuclear receptor based leads

Published: 28-Mar-2007
Regulatory

UK-based Peakdale Molecular has entered into an agreement with EnBioTec Laboratories Co, based in Tokyo, Japan, to co-develop nuclear receptor based lead compounds for drug discovery.


UK-based Peakdale Molecular has entered into an agreement with EnBioTec Laboratories Co, based in Tokyo, Japan, to co-develop nuclear receptor based lead compounds for drug discovery.

EnBioTec Laboratories has developed the Receptor Cofactor Assay System (RCAS) to investigate the interactions between nuclear hormone receptors, co-factors, and ligands. The system is cell-free, highly sensitive and is able to distinguish between agonist and antagonist compounds.

Peakdale Molecular will provide a targeted set of compounds for RCAS and functional assay testing and will work with EnBioTec to custom synthesize novel compounds based on the subsequent test results.

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