Evotec Neurosciences and Takeda enter into drug discovery alliance

Published: 1-Aug-2003

German company Evotec Neurosciences (ENS), a subsidiary of Evotec OAI, has entered into a four-year collaboration in the area of Alzheimer's disease (AD) with Takeda Chemical Industries, of Osaka in Japan.


German company Evotec Neurosciences (ENS), a subsidiary of Evotec OAI, has entered into a four-year collaboration in the area of Alzheimer's disease (AD) with Takeda Chemical Industries, of Osaka in Japan.

The two companies aim to identify and validate novel targets relating to different aspects of the causes and progression of AD, with the goal of developing innovative small molecule therapeutics.

ENS will grant Takeda access to its proprietary database of Alzheimer's disease-related targets, and further validate selected target candidates for downstream drug discovery programmes. Takeda will make payments to Evotec Neurosciences of up to €20m covering database access fees, research funding and milestone payments relating to the selection of targets for further drug discovery. Substantial milestones would also be payable on the successful clinical development of compounds acting on selected targets.

'We are delighted to start this extensive collaboration with Takeda,' said Dr John Kemp, ceo of Evotec Neurosciences. 'It is a major validation of Evotec Neurosciences' innovative work to identify and validate drug targets to prevent or treat Alzheimer's disease, which affects millions of people in the developed world and is becoming an ever-increasing challenge as the population ages.'

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