FlowCAT offers flexible fixed-bed hydrogenation

Published: 22-Mar-2010
Manufacturing

Bench-top reactor produces results from millilitres of product

HEL, an international group of companies supplying process tools for the pharmaceutical industry, has introduced the FlowCAT continuous flow bench-top reactor, which is said to be a flexible and cost-effective choice in lab-scale fixed-bed hydrogenation.

HEL, headquartered in Borehamwood, Hertfordshire, UK, has developed a system that delivers high-pressure flow chemistry, with the flexibility to tune hydrogenation conditions to suit the chemistry.

The system design allows for rapid screening of process conditions, which is useful in the early stage generation of API intermediates, where the behaviour and chemistry of the species may be an unknown.

The FlowCAT system is capable of producing results from just a few millilitres of product, but retains the ability to ramp up production volumes once ideal conditions are identified.

At the heart of the system is a tubular reactor with a standard 3mL or 12mL isothermal reaction zone. The system operates up to 400°C and 200Bar. Any heterogeneous catalyst can be used and users can pack their own columns. The wide-bore reactor removes any propensity for blockages and further extends the reliability of the system, the company says.

See more

You may also like

Manufacturing

Bracco enters cell therapy manufacturing with microbubble-based cell selection technology

Read more
Bracco Imaging is expanding into cell therapy manufacturing with a bead-free cell selection and activation technology based on its clinically validated microbubble platform

Trending Articles

  1. You need to be a subscriber to read this article.
    Click here to find out more.
    Overcoming the hurdles of strategic market expansion Ramprasad Kaparaboyena, Regulatory Affairs Manager and QP for Pharmacovigilance at Gaelic Laboratories, discusses how to overcome the challenges of expanding your pharma market into new global regions
  2. Vetter Pharma to build new manufacturing site in Germany as part of €1.5bn global expansion plan The company has submitted a building permit application for a new commercial manufacturing facility in Saarland, Germany, with construction set to begin in Q2 2026 and operations planned for 2031
  3. Drug-loaded pellets: unlocking flexible oral dosage design with modern pelletisation technologies Produced using advanced extrusion–spheronisation technologies such as GEA’s NICA systems, drug-loaded pellets are gaining traction as a flexible and scalable oral solid dosage platform that enhances release control, patient outcomes and manufacturing efficiency
  4. LabIndex - Sourcing solutions powered by a network of world-class suppliers Labtex states: "Using our experience and negotiating power, we can speedily source and procure virtually any type of laboratory equipment or consumables at competitive prices."
  5. New thermal inkjet printer expands AM Labels’ coding portfolio M2 system delivers high resolution variable data printing at production-line speeds

Upcoming event

High Shear = Mixing Success

19 February 2026 | Virtual See all

You may also like

Manufacturing

Bracco enters cell therapy manufacturing with microbubble-based cell selection technology

Bracco Imaging is expanding into cell therapy manufacturing with a bead-free cell selection and activation technology based on its clinically validated microbubble platform
Manufacturing

New manufacturing line from Adragos granted regulatory approval from Swissmedic

The approval of the new, state-of-the-art facility follows a comprehensive modernisation programme in 2024/2025 that has focussed on ensuring the future-readiness of the plant
Manufacturing

Freudenberg Medical launches new hydrophilic coating LUBRITEQ

The launch comes alongside a comprehensive suite of associated development and manufacturing services designed to remove commercial barriers and enable long-term, trust-based partnerships
Manufacturing

The REACTEX range - cutting-edge components, unmatched precision

Utilising cutting-edge components from leading UK and German manufacturers, the REACTEX range of interchangeable glass reactors offer the following:
Manufacturing

Drug-loaded pellets: unlocking flexible oral dosage design with modern pelletisation technologies

Produced using advanced extrusion–spheronisation technologies such as GEA’s NICA systems, drug-loaded pellets are gaining traction as a flexible and scalable oral solid dosage platform that enhances release control, patient outcomes and manufacturing efficiency
Manufacturing

Vetter Pharma to build new manufacturing site in Germany as part of €1.5bn global expansion plan

The company has submitted a building permit application for a new commercial manufacturing facility in Saarland, Germany, with construction set to begin in Q2 2026 and operations planned for 2031
Manufacturing

Torque of the town - Powerful overhead stirrers from Caframo Lab Solutions

In the UK, Labtex proudly supply a powerful range of overhead stirrers and quality accessories from trusted partners at Caframo Lab Solutions
Subscribe now