From injection to ingestion: can yeast make vaccines more accessible?

Published: 13-Feb-2026

As global vaccination coverage declines and distribution challenges persist, researchers are exploring edible yeast-based vaccines as a simpler, more scalable alternative to injections

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The idea of consuming a vaccine rather than receiving it by injection may sound implausible.

Yet scientists from Vilnius University Life Sciences (VU LSC) Center and the US National Cancer Institute are exploring yeast-based oral vaccines as a potential way to make immunisation more accessible, affordable and acceptable worldwide.

Their work raises broader questions about how vaccines could be produced and delivered in the future.

Is injection the only way to vaccinate?

In recent years, the scientific community has increasingly acknowledged that even when effective and safe vaccines exist, their accessibility often remains insufficient.

As doctoral researcher Emilija Vasiliūnaitė (pictured) explains, the reasons are diverse — ranging from complex, costly manufacturing processes to logistical challenges. 

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