Lonza expansion in UK
As part of Lonza's worldwide demand-driven manufacturing capacity expansion strategy, the company has extended its UK clinical-scale mammalian manufacturing capacity in Slough.
As part of Lonza's worldwide demand-driven manufacturing capacity expansion strategy, the company has extended its UK clinical-scale mammalian manufacturing capacity in Slough.
The investment totals approximately CHF14m (£6.1m) and is in response to increased worldwide customer demand for mammalian-derived biotherapeutics and the increasing number of products requiring clinical-scale manufacture.
The investment will allow the installation of a 500-litre stirred tank bio-reactor system with associated inoculum expansion area, media preparation and primary recovery capabilities. In addition, two purification suites will be created that will be used to meet the increased downstream requirements resulting from the new bioreactor and from the increasing product titres being realised with Lonza's GS expression technology. The additional fermentation capacity is scheduled to be on line in the fourth quarter of 2006.
Lonza is currently installing an additional 20,000-litre bioreactor train within its existing large-scale mammalian manufacturing facility in Portsmouth, New Hampshire, US, to be on line in mid-2006, and is building a commercial-scale biopharmaceutical manufacturing facility that includes two 15,000-litre microbial production trains in Visp, Switzerland.