New oral dose excipient aids controlled release

Published: 14-Jul-2008

A pharmaceutical excipient for oral dosage drug formulations that enables improved delivery of active pharmaceutical ingredients, has been added to the family of cellulose esters marketed by the Eastman Chemical Company.

A pharmaceutical excipient for oral dosage drug formulations that enables improved delivery of active pharmaceutical ingredients, has been added to the family of cellulose esters marketed by the Eastman Chemical Company.

Eastman Cellulose Acetate (CA-320S NF/EP) is particularly useful in controlled-release applications involving membrane release or matrix release, says the company. When used for controlled release applications, CA-320S aids in drug delivery by releasing the drug in the body at a controlled rate and over a predictable period of time.

CA-320S is the newest member of the Eastman family of cellulose esters for pharmaceutical applications that includes CA-398-10NF/EP, CAB 171-15 NF, and CA-320S NF/EP. Each has different physical properties and with the addition of CA-320S, formulators can have greater flexibility in designing drug delivery systems for targeted and controlled, sustained, or extended release.

CA-320S NF/EP is made under current good manufacturing conditions (cGMP) for oral dose pharmaceutical applications and meets the requirements of the National Formulary (NF) and European Pharmacopeia (EP).

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