Chip holder allows direct coupling of microfluidic chips

Published: 26-Nov-2010

Connection provides minimal disruption to fluid flow

The Mitos Double Chip Holder H from Dolomite, a specialist in microfluidic devices based in Royston, Hertfordshire, UK, allows direct interfacing of two microfluidic chips with accurate micro-channel to micro-channel connection via a precision perfluoroelastomer gasket. Once aligned the connection provides minimal disruption to the fluid flow.

Designed for use with the Mitos Edge Connector 4-way, the Mitos Double Chip Holder H provides eight fluidic connections to 1.6mm OD tubing.

Dolomite says the product is quick to connect and disconnect and operates over a temperature range from -15⁰C to 150⁰C and a pressure range up to 10bar.

One key application of the Mitos Double Chip Holder H is the generation of double emulsions, which have applications in the pharmaceutical industry, for example allowing an active ingredient or cell to be enclosed inside a protective outer shell.

Creating a double emulsion requires both hydrophobic and hydrophilic surfaces in different parts of the system, which in a single device can be complex and expensive to achieve. The Mitos Double Chip Holder H allows direct coupling of a hydrophobic chip and a hydrophilic chip, enabling users to generate both water-oil-water and oil-water-oil droplets by simply switching the chips around.

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