Pulseless liquid flow provides optimum smoothness

Published: 26-Aug-2010

Ideal for droplet formation in microfluidic applications

Dolomite’s Mitos P-Pump microfluidic system provides a pulseless liquid flow, using a precise pressure-driven pumping mechanism.

This mechanism is ideal for applications such as compartmentalised chemistry and alginate polymerisation systems, which necessitate the stable formation of oil-in-water or water-in-oil droplets, says the Royston, Hertfordshire, UK-based firm.

Because size consistency is key to obtaining accurate and repeatable results, Dolomite has carried out a number of tests to compare the size consistency of droplets formed by the Mitos P-Pump with market leading syringe pumps. Droplets of water-in-oil were generated on a 100µm X-Junction, using each of the pump technologies. The droplet diameter from a continuous stream was measured using image analysis software.
Dolomite has carried out tests to compare the size and consistency of droplets

Dolomite has carried out tests to compare the size and consistency of droplets

The resulting data demonstrated that the Mitos P-Pump provides a coefficient of variation in the droplet diameter of less than 0.6%, compared with 5.5% for the leading syringe pump. Its precise pressure-driven pumping mechanism delivers liquid with a smooth and even flow, whereas even the best motor drives and mechanics of a syringe pump have slight non-linearities, which cause unwanted pulsation, Dolomite says. The Mitos P-Pump technology therefore provides the best solution for droplet formation applications.

You may also like