Sartorius adds BIOSTAT Cplus lab bioreactor for process development to portfolio


The sterilisable-in-place system is equipped with a DCU controller

Sartorius Stedim Biotech’s BIOSTAT Cplus stainless steel fermenter/bioreactor is for the cultivation of micro-organisms and cell cultures. Typical applications include process development for the production of biopharmaceuticals, vaccines, biofuels and secondary metabolites, the optimisation of batch, fed-batch, continuous and perfusion processes, as well as scale-up and scale-down experiments.

The Sterilisable-In-Place (SIP) system is equipped with a DCU controller and other functions such as gravimetric feed control, advanced DO controller and integrated off-gas measurement. The culture vessels are supplied with operating volumes of 5, 10, 15, 20 and 30 litres.

The BIOSTAT Cplus features a modular design that allows for individual system configuration to meet specific requirements. For example, additional functions are available, such as automatic pressure control or integrated off-gas measurement, as well as re-sterilisable valves and sterile sampling kits. The culture vessel can be sterilised with electro or steam heating, which allows the fermenter/bioreactor to be integrated into existing infrastructure easily and cost-effectively.

The company says the compact design of the system saves valuable laboratory space; rollers under the supply unit ensure mobility and allow the system to be moved around to other labs while offering easy, unimpeded access to clean the floor underneath.

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The DCU controller offers touch screen operation that is said to be easy and intuitive and also reduces the risks of faulty operation while shortening the learning time when training new operators. New functions such as the 'advanced DO controller' and automatic sequences for sterilisation and the pressure hold test ensure optimal process control and a high degree of safety.