Sartorius offers fast, easy and reliable sample preparation with Claristep

The Claristep station consists of a base, a lid and an exchangeable tray for easy and accurate positioning of sample vials and filter units

Sartorius adds the Claristep system to its portfolio

Preparing samples by clarification is an essential step prior to nearly all analytical techniques, such as high pressure liquid chromatography (HPLC). This filtration step to eliminate particles is crucial for maintaining the integrity of chromatography columns and for maximising their operating life. In addition, as the sensitivity of automated analytical instruments continues to improve, they increasingly require less volume to operate to maximise throughput.

Fast small-volume clarification that does not add leachables or extractables to the original sample is indispensable for achieving the best analytical results.

To meet these requirements, German pharma and lab equipment supplier Sartorius has developed a new, easy-to-use and straightforward filtration setup. The manually operated Claristep filtration system consisting of a station and filter units offers a novel way for clarifying samples prior to analysis, the firm says.

The Claristep station consists of a base, a lid and an exchangeable tray for easy and accurate positioning of sample vials and Claristep filter units. The patent-pending design features unique grooves in the station’s lid and matching guide ridges on Claristep filter units to enable correct alignment and convenient handling of the system. The grooves automatically guide the filter unit caps into the correct positions for simultaneous and accurate cap closure.

Claristep enables up to eight samples to be simultaneously filtered – without needing any power supply or a vacuum/pressure source. Single-use Claristep filter units with RC membranes are for sample volumes of 60–600 µL. Their hold-up volume is less than 30 µL. The units are particularly for solvents and aqueous solutions and provide maximum chemical compatibility as well as exceptionally low non-specific binding of analytes, the firm says.

The contact time of the samples with the filters and the caps is very short, ensuring optimal, contamination-free results. Filtrates are collected in any 12 × 32 mm outer diameter vials of the user’s choice based on the analytical method to be performed.

Companies