Sartorius offers new crossflow filter device for biotechnological applications

Particularly for use in membrane screening and small-volume process development

Sartocon Slice 50 is offered as an encapsulated and ready-to-use crossflow module

Sartorius Stedim Biotech (SSB) has added the single-use ultrafilter Sartocon Slice 50 to its extensive portfolio. The new crossflow filter device is for use in biotechnological applications, especially for membrane screening and small-volume process development.

Sartocon Slice 50 is offered as an encapsulated and ready-to-use crossflow module with a filter area of 50cm2 and a wide variety of molecular weight cutoffs. The cGMP validated self-contained unit eliminates the need for a compression holder and is available in a choice of two polymers, the firm says.

The Hydrosart membrane is a stable polymer suitable for a broad pH range and can be depyrogenated using NaOH at elevated temperatures. It is extremely hydrophilic, making it non-protein-binding and virtually non-fouling, and delivers an exceptional high flux, the firm says.

The polyethersulfone membrane (PESU), which is well established in the biotechnological and pharmaceutical industries, is a stable polymer that is suitable for a broad pH and temperature range.

The firm says a major benefit of the new device is its linear scalability, along with identical materials of construction, which eases transfer of process development results to the next scale up level.

Sartocon Slice 50 can be interfaced with SSB’s recently launched Sartoflow Smart benchtop crossflow system, as well as with many other laboratory-scale filtration systems.

Companies