Astex and Mitsubishi in discovery agreement
UK structure-based drug discovery company Astex Technology has entered into a structural biology research agreement with Mitsubishi Pharma Corporation to facilitate the rapid design and development of drug candidates. The collaboration will focus on solving novel human cytochrome P450 crystal structures that will be used in optimisation of Mitsubishi's compounds, and improve potential for their clinical success.
Under the terms of the agreement, financial details of which were not disclosed, Astex will apply its proprietary X-ray crystallography technologies to obtain crystal structures of cytochrome P450s complexed to Mitsubishi's compounds.