Avid Bioservices is first to win contract manufacturing status
A US-based company in California has become the first to be awarded contract manufacturer status of a cell line protein technology.
A US-based company in California has become the first to be awarded contract manufacturer status of a cell line protein technology.
Avid Bioservices, a subsidiary of Peregrine Pharmaceuticals Inc, has signed an agreement with DSM and Crucell for licensees of the PER.C6 cell line located in the western part of the US.
Karen King, president of DSM Biologics, said: "We are confident that Avid's excellent reputation and service level will be instrumental in making the PER.C6 technology available to licensees on the West Coast, bringing our technology to a wider regional base as we continue to grow globally."
Crucell's PER.C6 technology platform has been developed for the large-scale manufacture of biopharmaceutical products such as recombinant proteins including monoclonal antibodies.
Steven King, president of Avid Bioservices, said: "We are honoured to achieve the distinction of being the first pre-approved US-based CMO to manufacture proteins and antibodies using the PER.C6 cell line. The PER.C6 technology is recognised throughout our industry as providing important advantages compared to other platforms, including serum-free medium, scalability and high productivity levels making the system an ideal fit for Avid."
Crucell and DSM announced a breakthrough in the production of IgG antibodies using Crucell's PER.C6 technology. By employing the PER.C6 human cell line and DSM's proprietary XD technology, a record yield of over 27 grams per litre has been achieved.
The PER.C6 technology platform has been developed for the large-scale manufacture of biopharmaceutical products such as recombinant proteins, including monoclonal antibodies. Compared to conventional production technologies, the strengths of PER.C6 technology lie in its excellent safety profile, scalability and productivity under serum-free culture conditions.
Avid Bioservices provides a comprehensive range of cGMP manufacturing services for the biotechnology and biopharmaceutical industries.