The demand for peptide-based active ingredients continues to increase—both in pharmaceutical research and in commercial production. For many years, Buchiglas has been providing reliable reactor systems for solid phase peptide synthesis (SPPS), supporting customers worldwide with tailor-made technology for every stage of production.
Solid phase peptide synthesis (SPPS) is an established method for peptide synthesis. It is a process in which a peptide anchored to an insoluble polymer (resin) is assembled by the successive addition of protected amino acids forming its sequence. It is widely utilised for synthesising peptides efficiently and reliably – from lab to commercial scale.
At Buchiglas, we understand the critical role that reactor technology plays in achieving successful synthesis results. With decades of experience and a market leading position in peptide synthesis, we provide tailored solutions to run both manual and fully automated processes.
Our systems range from standardised to customised solutions and are available in scales from lab trough pilot/kilo lab up to commercial production volumes (5 – 500 litres). All ensuring exceptional consistency and reproducibility of synthesis results. All systems are cGMP compliant and are suitable for the production of high-quality peptide active pharmaceutical ingredients (APIs).
A Partner for Your Synthesis Processes
Buchiglas stands not only for robust and precise reactor systems but also for comprehensive consulting, integration, and service. Whether process development, technology transfer, or GMP production – our solutions are designed to make your synthesis processes safe, efficient, and sustainable in the long term.
Contact us to learn more about our SPPS solutions – from feasibility studies to production-ready systems: Peptide Synthesizer Reactor Solutions for R&D & Production: Büchiglas
Image credit: Büchi AG