Genevac's Model DD-4X centrifugal evaporator has been used to address the sample integrity and physical storage problems associated with compound library maintenance by a pharmaceutical company.
The pharmaceutical company uses a high throughput process to produce compound libraries as dry films that have been validated for long-term storage. The compounds were solubilised, reformatted from 96- to 384-well plates and then dried down using a Genevac DD-4X centrifugal evaporator for storage at room temperature.
The high capacity of the Model DD-4X was shown to facilitate sample-safe evaporation of 16 384-well plates to dryness in only 25 minutes at 40°C. The dry film methodology reduces the time for compound preparation and produces enough assay ready sets of dry film plates for at least 10 screens.
The Model DD-4X is a high-performance centrifugal evaporator system that handles the wide range of sample types and formats encountered in pharmaceutical laboratories.
Genevac, a division of SP Industries, was founded in 1990. Headquartered in Ipswich, UK, the company offers evaporators to suit almost any solvent removal application, purchasing budget or productivity requirement.