Agilent secures US patent

For a process that applies a porous shell to particles in LC

Agilent has received a US patent for the coacervation process used to manufacture Poroshell 120 silica

Agilent Technologies has been awarded a US patent for a process that applies the superficially porous shell to particles in its Poroshell 120 high-performance liquid chromatography (HPLC) columns.

The Santa Clara, California-based measurement and chemical analysis company said the patent was issued for the unique coacervation process used to manufacture Poroshell 120 silica. This applies the superficially porous shell to the particles in a single step, replacing a multi-layering procedure, which is said to reduce variation between columns for more reproducible results.

Poroshell 120 columns make the high speed and high resolution of sub-two-micron separations available to users of any mainstream LC instrument, including conventional HPLC. The columns also enhance the performance of UHPLC systems, up to 600 bar, enabling chromatographers to optimise the performance of Agilent’s new 1200 Infinity Series, which offers 600-bar capabilities as a standard feature.

‘This simpler process delivers real benefits to our customers because it reduces variability in the chromatography workflow, and that is always a good thing,’ said Helen Stimson, Agilent vice president, global consumables for life sciences and chemical analysis.

Agilent introduced superficially porous shell particle technology in 2001 with the Poroshell 300 HPLC column for biomolecule separations, and has reinvented the technology using coacervation as a key differentiator between Poroshell 120 columns and competitive offerings.

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