This technique enables detailed molecular fingerprinting, facilitating the analysis of protein structure, aggregation and stability, which are critical parameters in the production of biotherapeutics.
Raman spectroscopy is increasingly utilised to monitor critical quality attributes (CQAs) during upstream and downstream processes, including cell culture media optimisation, formulation development and real-time process monitoring within Quality by Design (QbD) frameworks.
Not yet a Subscriber?
This is a small extract of the full article which is available ONLY to premium content subscribers. Click below to get premium content on Manufacturing Chemist.
Subscribe now Already a subscriber? Sign in here.