Pilot XT helps drive aqueous tablet coating process
Aqueous film coating is the leading technology in tablet coating, but the heat required places more stringent demands on the process parameters during the coating cycle, and in some situations where the active principal is heat sensitive there may be only a small window of operation where the process is stable.
Aqueous film coating is the leading technology in tablet coating, but the heat required places more stringent demands on the process parameters during the coating cycle, and in some situations where the active principal is heat sensitive there may be only a small window of operation where the process is stable.
The new Pilot XT aqueous coating pan from UK-based Profile Automation controls the process by means of three process-tuned controllers - inlet temperature: heater control; exhaust temperature: pump control; and pan depression: airflow control. This technology provides ensures that each coating run is reproducible and so provides reliable data prior to scale-up.
The Pilot XT was designed to meet the demands of Design of Experiments (DOE) process development trials. DOE technology specifies that the designated process or material variables must be accurately reproduced to generate valid data.