Affiris to develop Parkinson's vaccine

Published: 17-Dec-2008
Sustainability Research & Development

Affiris, an Austrian developer of peptide-based vaccines for the treatment of Alzheimer's disease, atherosclerosis and other diseases, has started pre-clinical development of a Parkinson's vaccine.


Affiris, an Austrian developer of peptide-based vaccines for the treatment of Alzheimer's disease, atherosclerosis and other diseases, has started pre-clinical development of a Parkinson's vaccine.

The vaccine, known as PD01, can be used to target a specific protein that is closely associated with the causes of this degenerative neurological disease. The vaccine is based on the company's Affitome technology, which, among other things, has already been used to develop two Alzheimer's vaccines, which are currently in phase I clinical testing.

On successful conclusion of this preclinical evaluation, initial clinical testing could start in 2010/11. The Parkinson's vaccine specifically targets the alpha-synuclein (alpha-syn) protein, which is considered to be a key contributory element in Parkinson's disease.

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