Almac launches histone reagents catalogue and custom synthesis service

Published: 17-Sep-2012

Histone reagents will prove a highly valuable tool for research in the field of epigenetics


Almac has launched a new reagent offering based on the provision of homogeneous full length histones with defined patterns of modification. The histone reagents will prove a highly valuable tool for researchers seeking to prosecute key drug targets in the field of epigenetics.

Almac’s unique array of platform technologies for the chemical synthesis of proteins enables the provision of pure full-length natural histones containing a wide variety of post-translational modifications at any specified site(s) within the protein. The reagents are set to be offered through a catalogue of modified histones and additionally as a custom synthesis service to meet bespoke customer demands.

Almac believes this will provide the epigenetic research community with a unique source of enabling research tools. The modified histone reagent provision complements Almac’s growing range of FLEXYTE FLT assays for epigenetic targets.

‘This is a first class example of how Almac can harness its unique protein synthesis capability to provide a much needed source of tools to the epigenetic research field,’ said Dr Charles Shields, Vice President of Peptide and Protein Technologies at Almac. ‘I am delighted that we are able to offer such capabilities.’

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