Improving ADC selection with AI-enabled assays

Published: 23-Apr-2025

In this article, Dr Rob Monroe, Chief Medical Officer at Leica Biosystems, discusses how diagnostics companies are working with researchers to develop novel assays leveraging digital imaging and analysis to identify patients for treatment with specific ADCs

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Antibody-drug conjugates (ADCs) are revolutionising oncology treatments because of their ability to precisely target tumours with toxic payloads that kill cancer cells without causing significant harm to normal tissues.

ADC developers have dramatically improved upon the original technology developed more than 20 years ago by further developing the components of the drugs, including the monoclonal antibodies, the cytotoxic payloads and the linkers connecting the payloads to the antibodies. 

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