Latest QuadraPure scavenger targets trace contaminants
Pharma technologies company Reaxa has added QuadraPure C to its resin-based scavenger range, complementing the existing metal clean-up range.
Pharma technologies company Reaxa has added QuadraPure C to its resin-based scavenger range, complementing the existing metal clean-up range.
QuadraPure C offers a totally synthetic, porous, high surface area, non-functional carbon-based material for adsorption of small molecule organic contaminants, the company says.
Key applications for QuadraPure C will include removal of colour, trace impurities and odour from APIs, building blocks and speciality chemicals. Additional roles will include removal of trace organic impurities from aqueous solutions and waste streams, giving cleaner products and effluents.
Compared with granular activated carbons, QuadraPure C is said to have improved application and easier handling characteristics, due to its large regular spherical particles, well defined pore structure and good mechanical stability. These characteristics make it ideal for use in fixed beds with no carry-over of fine particulates - so avoiding reactor and product contamination.
It will enable process intensification in either batch or flow processes with its good filtration characteristics, high adsorption capacity, fast flow rates at low back pressure and availability in loose form or pre-packed cartridges compatible with existing lab and process equipment.
QuadraPure C beads are spheroid, neutral and mechanically and thermally stable up to 300°C. They are free-flowing solids and free of dust and solvent. As for other QuadraPure products, Reaxa will supply a Regulatory Support File to assist pharma customers with cGMP compliance.
'QuadraPure C plays to Reaxa's 'easier, faster and cleaner processes' agenda in a logical extension to our versatile range of resin-based metal catalyst and reagent scavengers,' said Reaxa's chief technology officer Dr David Pears. 'We're excited about the potential for this product and have already demonstrated its utility in several projects including removal of low molecular weight impurities such as odorous thiols from peptides.'