Mettler Toledo has combined its InPro6800 dissolved/gaseous oxygen sensors with its M300 two-channel multi-parameter transmitter to help pharma manufacturers improve the inertisation process.
After purification, biotechnologically manufactured vaccines are processed into a form ready for administration. This is achieved by adding certain compounds that enhance the vaccines" efficacy and the body's tolerance when they are injected. The stability of certain compounds requires careful inertisation of the formulations.
Inertisation consists of injecting an inert gas, usually nitrogen, into a head space in order to displace the gas that is already there. The nitrogen is injected until the residual oxygen level reached is sufficiently low. Any risks associated with the influence of oxygen are thus totally under control.
Mettler Toledo's system measures gaseous and dissolved oxygen and features excellent stability of sensors and very low detection limits, the company says. It is autoclavable, sterilisable, compatible with existing process connections, and incorporates a multi-channel and multi-parameter transmitter.
The InPro6800 sensors provide precise oxygen control, even under the most rigorous conditions.
The M300 two-channel transmitter combines robustness and simplicity. A quick set-up menu guides users through installation and settings. It is possible to track gas and liquid phase oxygen, or oxygen and conductivity.